生物素文獻薈萃報告 — 2026 年 3 月

摘要

本月共收錄 生物素 相關文獻 3613 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）64 篇，RCT 23 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	64	1.8%
Level 2 (RCT)	23	0.6%
Level 3 (Clinical Trial)	10	0.3%
Level 4 (Observational)	8	0.2%
Level 5 (Review/Case Report/Other)	3508	97.1%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	2025	56.0%
immune	免疫調節	445	12.3%
metabolic	代謝	336	9.3%
cardiovascular	心血管	300	8.3%
anti_aging	抗衰老	281	7.8%
energy	活力	258	7.1%
cognitive	認知功能	255	7.1%
musculoskeletal	肌肉骨骼	198	5.5%
digestive	消化	163	4.5%
skin	皮膚	115	3.2%
sexual	性功能	43	1.2%

成分搭配統計

成分	文獻數
EPA	451
iron	405
NAC	106
fiber	58
calcium	51
collagen	41
stem cell	40
glutathione	37
zinc	33
magnesium	16

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
EPA + iron	55
NAC + iron	19
EPA + NAC	17
calcium + iron	12
EPA + collagen	11
exosome + exosomes	11
EPA + calcium	10
glutathione + iron	10
fiber + iron	9
EPA + fiber	8

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	免疫調節	代謝	心血管	抗衰老	活力
EPA	451	207	80	53	55	46	38
iron	405	231	60	33	22	26	34
NAC	106	59	17	9	13	3	8
fiber	58	23	6	6	4	5	9
calcium	51	20	6	9	2	5	11
collagen	41	-	16	6	4	9	1
stem cell	40	5	15	5	2	6	1
glutathione	37	10	16	11	11	6	1

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	46	1.3%
Systematic Review	18	0.5%
RCT	23	0.6%
Clinical Trial	10	0.3%
Observational	8	0.2%
Review	87	2.4%
Case Report	54	1.5%
Other	3367	93.2%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. The association between toll-like receptor gene polymorphism and Helicobacter pylori infection risk: A systematic review and meta-analysis. — Medicine, 2026-02-20
   • 功效分類：other
2. Health-related quality of life after free flap reconstruction of maxillary defects: a systematic review and meta-analysis. — Oral oncology, 2026-03-18
   • 功效分類：other
3. Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra-Renal Systemic Lupus Erythematosus - A Systematic Review & Meta-analysis. — Arthritis care & research, 2026-03-09
   • 功效分類：other
4. Timing-dependent effects of melatonin supplementation on exercise performance and exercise-induced muscle damage: a systematic review and meta-analysis. — Frontiers in nutrition, 2026-01-01
   • 功效分類：musculoskeletal
5. Comparative Efficacy and Safety of Hybrid Endoscopic Submucosal Dissection for Colorectal Neoplasia: A Systematic Review and Meta-Analysis. — JGH open : an open access journal of gastroenterology and hepatology, 2026-03-01
   • 功效分類：other

Level 2 證據（RCT）

1. Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery: A Randomized Clinical Trial. — JAMA network open, 2026-03-02
   • 功效分類：cardiovascular, immune
2. Efficacy of vaginal androgen combined with pelvic floor muscle training for stress urinary incontinence in postmenopausal women: a randomized-controlled trial. — The Canadian journal of urology, 2026-02-28
   • 功效分類：musculoskeletal
3. Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention. — Lancet (London, England), 2026-03-21
   • 功效分類：anti_aging, metabolic, digestive
4. Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study. — Drug design, development and therapy, 2026-01-01
   • 功效分類：cardiovascular
5. Conservative versus conventional oxygenation target in children admitted in PICU: a randomized controlled trial. — European journal of pediatrics, 2026-03-23
   • 功效分類：other

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