生物素文獻薈萃報告 — 2026 年 4 月

摘要

本月共收錄 生物素 相關文獻 4094 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）73 篇，RCT 25 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	73	1.8%
Level 2 (RCT)	25	0.6%
Level 3 (Clinical Trial)	16	0.4%
Level 4 (Observational)	11	0.3%
Level 5 (Review/Case Report/Other)	3969	96.9%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	2315	56.5%
immune	免疫調節	496	12.1%
metabolic	代謝	379	9.3%
cardiovascular	心血管	321	7.8%
anti_aging	抗衰老	317	7.7%
energy	活力	293	7.2%
cognitive	認知功能	290	7.1%
musculoskeletal	肌肉骨骼	225	5.5%
digestive	消化	182	4.4%
skin	皮膚	131	3.2%
sexual	性功能	44	1.1%

成分搭配統計

成分	文獻數
EPA	507
iron	461
NAC	122
fiber	67
calcium	56
stem cell	47
collagen	47
glutathione	41
zinc	38
creatine	18

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
EPA + iron	61
NAC + iron	24
EPA + NAC	18
calcium + iron	15
EPA + collagen	13
exosome + exosomes	12
EPA + fiber	10
EPA + calcium	10
EPA + stem cell	10
glutathione + iron	10

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	免疫調節	代謝	抗衰老	心血管	肌肉骨骼
EPA	507	236	89	60	55	61	41
iron	461	262	70	41	32	22	20
NAC	122	68	18	12	4	13	3
fiber	67	29	6	6	5	4	12
calcium	56	20	8	10	5	2	13
stem cell	47	7	18	5	7	3	14
collagen	47	-	17	6	10	4	12
glutathione	41	12	16	12	7	11	2

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	53	1.3%
Systematic Review	20	0.5%
RCT	25	0.6%
Clinical Trial	16	0.4%
Observational	11	0.3%
Review	97	2.4%
Case Report	60	1.5%
Other	3812	93.1%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. The association between toll-like receptor gene polymorphism and Helicobacter pylori infection risk: A systematic review and meta-analysis. — Medicine, 2026-02-20
   • 功效分類：other
2. Health-related quality of life after free flap reconstruction of maxillary defects: a systematic review and meta-analysis. — Oral oncology, 2026-03-18
   • 功效分類：other
3. Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra-Renal Systemic Lupus Erythematosus - A Systematic Review & Meta-analysis. — Arthritis care & research, 2026-03-09
   • 功效分類：other
4. Timing-dependent effects of melatonin supplementation on exercise performance and exercise-induced muscle damage: a systematic review and meta-analysis. — Frontiers in nutrition, 2026-01-01
   • 功效分類：musculoskeletal
5. Comparative Efficacy and Safety of Hybrid Endoscopic Submucosal Dissection for Colorectal Neoplasia: A Systematic Review and Meta-Analysis. — JGH open : an open access journal of gastroenterology and hepatology, 2026-03-01
   • 功效分類：other

Level 2 證據（RCT）

1. Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery: A Randomized Clinical Trial. — JAMA network open, 2026-03-02
   • 功效分類：cardiovascular, immune
2. Efficacy of vaginal androgen combined with pelvic floor muscle training for stress urinary incontinence in postmenopausal women: a randomized-controlled trial. — The Canadian journal of urology, 2026-02-28
   • 功效分類：musculoskeletal
3. Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention. — Lancet (London, England), 2026-03-21
   • 功效分類：anti_aging, metabolic, digestive
4. Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study. — Drug design, development and therapy, 2026-01-01
   • 功效分類：cardiovascular
5. Dexmedetomidine Plus Stellate Ganglion Block Improves Postoperative Sleep Quality in Elderly Hip Arthroplasty Patients: A Randomized Controlled Trial. — Drug design, development and therapy, 2026-01-01
   • 功效分類：other

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