生物素文獻薈萃報告 — 2026 年 6 月

摘要

本月共收錄 生物素 相關文獻 4583 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）81 篇，RCT 28 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	81	1.8%
Level 2 (RCT)	28	0.6%
Level 3 (Clinical Trial)	16	0.3%
Level 4 (Observational)	11	0.2%
Level 5 (Review/Case Report/Other)	4447	97.0%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	2631	57.4%
immune	免疫調節	527	11.5%
metabolic	代謝	421	9.2%
cardiovascular	心血管	360	7.9%
anti_aging	抗衰老	338	7.4%
energy	活力	334	7.3%
cognitive	認知功能	318	6.9%
musculoskeletal	肌肉骨骼	243	5.3%
digestive	消化	200	4.4%
skin	皮膚	139	3.0%
sexual	性功能	47	1.0%

成分搭配統計

成分	文獻數
EPA	554
iron	526
NAC	131
fiber	73
calcium	60
stem cell	52
collagen	51
zinc	45
glutathione	45
hyaluronic acid	20

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
EPA + iron	70
NAC + iron	26
EPA + NAC	18
calcium + iron	15
EPA + collagen	14
EPA + fiber	12
exosome + exosomes	12
EPA + calcium	11
fiber + iron	11
glutathione + iron	11

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	免疫調節	代謝	活力	抗衰老	心血管
EPA	554	256	96	65	46	61	66
iron	526	303	76	48	46	35	28
NAC	131	74	19	12	10	5	15
fiber	73	33	6	6	11	5	5
calcium	60	23	8	10	12	5	3
stem cell	52	10	19	5	1	7	3
collagen	51	-	18	7	2	10	4
zinc	45	29	1	2	8	1	3

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	58	1.3%
Systematic Review	23	0.5%
RCT	28	0.6%
Clinical Trial	16	0.3%
Observational	11	0.2%
Review	116	2.5%
Case Report	62	1.4%
Other	4269	93.1%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. The association between toll-like receptor gene polymorphism and Helicobacter pylori infection risk: A systematic review and meta-analysis. — Medicine, 2026-02-20
   • 功效分類：other
2. Health-related quality of life after free flap reconstruction of maxillary defects: a systematic review and meta-analysis. — Oral oncology, 2026-03-18
   • 功效分類：other
3. Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients with Extra-Renal Systemic Lupus Erythematosus - A Systematic Review & Meta-analysis. — Arthritis care & research, 2026-03-09
   • 功效分類：other
4. Timing-dependent effects of melatonin supplementation on exercise performance and exercise-induced muscle damage: a systematic review and meta-analysis. — Frontiers in nutrition, 2026-01-01
   • 功效分類：musculoskeletal
5. Comparative Efficacy and Safety of Hybrid Endoscopic Submucosal Dissection for Colorectal Neoplasia: A Systematic Review and Meta-Analysis. — JGH open : an open access journal of gastroenterology and hepatology, 2026-03-01
   • 功效分類：other

Level 2 證據（RCT）

1. Butorphanol decreased the median effective concentration of ropivacaine in ultrasound-guided interscalene brachial plexus block. — PloS one, 2026-01-01
   • 功效分類：other
2. Sivelestat and Incidence of Acute Respiratory Distress Syndrome After Cardiovascular Surgery: A Randomized Clinical Trial. — JAMA network open, 2026-03-02
   • 功效分類：cardiovascular, immune
3. Efficacy of vaginal androgen combined with pelvic floor muscle training for stress urinary incontinence in postmenopausal women: a randomized-controlled trial. — The Canadian journal of urology, 2026-02-28
   • 功效分類：musculoskeletal
4. Prevention of urinary stones with hydration: a randomised clinical trial of an adherence intervention. — Lancet (London, England), 2026-03-21
   • 功效分類：anti_aging, metabolic, digestive
5. Effects of Cipepofol on Cardiac Depolarization and Repolarization in Healthy Subjects: A Single-Center, Randomized, Placebo and Positive-Controlled Thorough QT Study. — Drug design, development and therapy, 2026-01-01
   • 功效分類：cardiovascular

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