鈣文獻薈萃報告 — 2026 年 4 月

摘要

本月共收錄 鈣 相關文獻 2179 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）58 篇，RCT 4 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	58	2.7%
Level 2 (RCT)	4	0.2%
Level 3 (Clinical Trial)	4	0.2%
Level 4 (Observational)	12	0.6%
Level 5 (Review/Case Report/Other)	2101	96.4%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	703	32.3%
immune	免疫調節	417	19.1%
musculoskeletal	肌肉骨骼	408	18.7%
cardiovascular	心血管	394	18.1%
anti_aging	抗衰老	335	15.4%
metabolic	代謝	332	15.2%
cognitive	認知功能	264	12.1%
energy	活力	176	8.1%
digestive	消化	91	4.2%
skin	皮膚	90	4.1%
sexual	性功能	25	1.1%

成分搭配統計

成分	文獻數
calcium	1789
EPA	275
iron	271
vitamin D	131
magnesium	97
stem cell	81
NAC	65
zinc	61
fiber	55
collagen	50

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
EPA + calcium	245
calcium + iron	222
calcium + vitamin D	122
calcium + magnesium	89
calcium + stem cell	71
calcium + zinc	59
NAC + calcium	55
calcium + fiber	46
calcium + collagen	45
EPA + iron	42

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	肌肉骨骼	免疫調節	心血管	代謝	抗衰老
calcium	1789	510	353	369	355	301	305
EPA	275	75	59	68	56	52	38
iron	271	106	43	71	33	33	26
vitamin D	131	29	76	22	14	45	24
magnesium	97	44	23	8	12	17	8
stem cell	81	13	29	23	15	7	16
NAC	65	32	4	9	7	6	8
zinc	61	22	11	14	10	13	5

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	28	1.3%
Systematic Review	30	1.4%
RCT	4	0.2%
Clinical Trial	4	0.2%
Observational	12	0.6%
Review	243	11.2%
Case Report	92	4.2%
Other	1766	81.0%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. Long-Term Safety and Effectiveness of Calcium Channel Blockers in Hypertension: A Systematic Review. — Drug, healthcare and patient safety, 2026-01-01
   • 功效分類：cardiovascular, metabolic, musculoskeletal
2. Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review. — Equine veterinary journal, 2026-02-24
   • 功效分類：musculoskeletal
3. Effectiveness and safety of bone protective interventions to mitigate bone loss and skeletal fractures experienced by patients with non-metastatic breast cancer: a systematic review and meta-analysis. — Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026-02-16
   • 功效分類：musculoskeletal
4. Diagnosis and Management of Resistant Hypertension: A Review. — JAMA, 2026-03-23
   • 功效分類：cardiovascular, immune, metabolic
5. Surgical vs Non-surgical Chin Augmentation: A Systematic Review of Techniques Satisfaction, and Complications. — Aesthetic plastic surgery, 2026-02-19
   • 功效分類：musculoskeletal

Level 2 證據（RCT）

1. Creatine plus β-Hydroxy-β-Methylbutyrate supplementation is associated with preserved glutathione redox-balance and redox-function associations in older adults: a secondary analysis of a randomized crossover trial. — Biogerontology, 2026-02-19
   • 功效分類：musculoskeletal
2. Photographic Ridge Width Measurement After 2 Different Alveolar Ridge-Preservation Procedures: Clinical Study Analysis Part III. — The Journal of oral implantology, 2026-02-17
   • 功效分類：musculoskeletal, skin
3. Outcomes of Direct Pulp Capping After Carious Excavation of Deep Caries on Permanent Mature Teeth: An Ancillary Study Derived From A Randomised Clinical Trial. — European endodontic journal, 2025-12-01
   • 功效分類：anti_aging
4. Calcium Hydroxyapatite and Polymicronutrient Solution on Hand Rejuvenation: A Split-Hand, Randomized, Double-Blind Clinical and In Vitro Study. — Journal of cosmetic dermatology, 2026-02-01
   • 功效分類：anti_aging, metabolic, skin

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