鈣文獻薈萃報告 — 2026 年 6 月

摘要

本月共收錄 鈣 相關文獻 3111 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）85 篇，RCT 4 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	85	2.7%
Level 2 (RCT)	4	0.1%
Level 3 (Clinical Trial)	5	0.2%
Level 4 (Observational)	15	0.5%
Level 5 (Review/Case Report/Other)	3002	96.5%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	1014	32.6%
immune	免疫調節	600	19.3%
musculoskeletal	肌肉骨骼	577	18.5%
cardiovascular	心血管	569	18.3%
anti_aging	抗衰老	490	15.8%
metabolic	代謝	468	15.0%
cognitive	認知功能	379	12.2%
energy	活力	249	8.0%
skin	皮膚	132	4.2%
digestive	消化	130	4.2%
sexual	性功能	36	1.2%

成分搭配統計

成分	文獻數
calcium	2566
iron	389
EPA	380
vitamin D	183
magnesium	121
stem cell	101
NAC	98
fiber	78
collagen	75
zinc	73

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
EPA + calcium	340
calcium + iron	324
calcium + vitamin D	173
calcium + magnesium	112
calcium + stem cell	88
NAC + calcium	86
calcium + zinc	71
calcium + collagen	70
calcium + fiber	67
EPA + iron	54

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	肌肉骨骼	免疫調節	心血管	代謝	抗衰老
calcium	2566	734	510	528	512	423	451
iron	389	149	62	102	52	49	40
EPA	380	107	84	92	77	72	51
vitamin D	183	36	107	33	20	62	36
magnesium	121	58	26	8	15	19	13
stem cell	101	16	34	27	18	11	20
NAC	98	40	10	14	14	9	16
fiber	78	25	16	10	5	5	10

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	40	1.3%
Systematic Review	45	1.4%
RCT	4	0.1%
Clinical Trial	5	0.2%
Observational	15	0.5%
Review	352	11.3%
Case Report	121	3.9%
Other	2529	81.3%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. LncRNA DLEU1 as a novel therapeutic target and prognostic biomarker in various malignancies: a meta-analysis, bioinformatics analysis and systematic review. — Frontiers in oncology, 2026-01-01
   • 功效分類：other
2. Diet and nutrition in patients with neuromuscular disorders, as lifestyle factors affecting clinical parameters and quality of life: a narrative systematic review. — Nutrition research reviews, 2026-04-24
   • 功效分類：cardiovascular, immune, musculoskeletal
3. Long-Term Safety and Effectiveness of Calcium Channel Blockers in Hypertension: A Systematic Review. — Drug, healthcare and patient safety, 2026-01-01
   • 功效分類：cardiovascular, metabolic, musculoskeletal
4. Clinical and research applications of synthetic bone substitutes in equine veterinary medicine: A systematic review. — Equine veterinary journal, 2026-02-24
   • 功效分類：musculoskeletal
5. Effectiveness and safety of bone protective interventions to mitigate bone loss and skeletal fractures experienced by patients with non-metastatic breast cancer: a systematic review and meta-analysis. — Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026-02-16
   • 功效分類：musculoskeletal

Level 2 證據（RCT）

1. Creatine plus β-Hydroxy-β-Methylbutyrate supplementation is associated with preserved glutathione redox-balance and redox-function associations in older adults: a secondary analysis of a randomized crossover trial. — Biogerontology, 2026-02-19
   • 功效分類：musculoskeletal
2. Photographic Ridge Width Measurement After 2 Different Alveolar Ridge-Preservation Procedures: Clinical Study Analysis Part III. — The Journal of oral implantology, 2026-02-17
   • 功效分類：musculoskeletal, skin
3. Outcomes of Direct Pulp Capping After Carious Excavation of Deep Caries on Permanent Mature Teeth: An Ancillary Study Derived From A Randomised Clinical Trial. — European endodontic journal, 2025-12-01
   • 功效分類：anti_aging
4. Calcium Hydroxyapatite and Polymicronutrient Solution on Hand Rejuvenation: A Split-Hand, Randomized, Double-Blind Clinical and In Vitro Study. — Journal of cosmetic dermatology, 2026-02-01
   • 功效分類：anti_aging, metabolic, skin

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