外泌體文獻薈萃報告 — 2026 年 2 月
摘要
本月共收錄 外泌體 相關文獻 2357 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）62 篇，RCT 10 篇。
證據等級分布
| 證據等級 |
文獻數 |
佔比 |
| Level 1 (Meta-Analysis/Systematic Review) |
62 |
2.6% |
| Level 2 (RCT) |
10 |
0.4% |
| Level 3 (Clinical Trial) |
7 |
0.3% |
| Level 4 (Observational) |
6 |
0.3% |
| Level 5 (Review/Case Report/Other) |
2272 |
96.4% |
功效分類統計
| 功效分類 |
中文 |
文獻數 |
佔比 |
| immune |
免疫調節 |
957 |
40.6% |
| other |
其他 |
644 |
27.3% |
| musculoskeletal |
肌肉骨骼 |
455 |
19.3% |
| anti_aging |
抗衰老 |
327 |
13.9% |
| cardiovascular |
心血管 |
289 |
12.3% |
| metabolic |
代謝 |
263 |
11.2% |
| cognitive |
認知功能 |
248 |
10.5% |
| skin |
皮膚 |
236 |
10.0% |
| digestive |
消化 |
147 |
6.2% |
| sexual |
性功能 |
45 |
1.9% |
| energy |
活力 |
44 |
1.9% |
成分搭配統計
| 成分 |
文獻數 |
| stem cell |
1033 |
| exosome |
501 |
| EPA |
489 |
| iron |
426 |
| exosomes |
425 |
| collagen |
125 |
| calcium |
43 |
| NAC |
31 |
| fiber |
30 |
| hyaluronic acid |
22 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 |
共同出現文獻數 |
| exosome + exosomes |
425 |
| EPA + stem cell |
289 |
| iron + stem cell |
176 |
| exosome + stem cell |
159 |
| exosomes + stem cell |
150 |
| EPA + exosome |
125 |
| EPA + iron |
123 |
| EPA + exosomes |
113 |
| exosome + iron |
108 |
| exosomes + iron |
91 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 |
總文獻 |
免疫調節 |
肌肉骨骼 |
其他 |
皮膚 |
抗衰老 |
心血管 |
| stem cell |
1033 |
410 |
273 |
266 |
113 |
154 |
83 |
| exosome |
501 |
248 |
95 |
102 |
86 |
76 |
87 |
| EPA |
489 |
256 |
156 |
79 |
71 |
78 |
63 |
| iron |
426 |
263 |
90 |
76 |
40 |
55 |
58 |
| exosomes |
425 |
211 |
84 |
90 |
75 |
62 |
77 |
| collagen |
125 |
54 |
46 |
- |
125 |
26 |
10 |
| calcium |
43 |
20 |
22 |
5 |
4 |
3 |
7 |
| NAC |
31 |
12 |
5 |
12 |
- |
4 |
6 |
研究類型分布
| 研究類型 |
文獻數 |
佔比 |
| Meta-Analysis |
24 |
1.0% |
| Systematic Review |
38 |
1.6% |
| RCT |
10 |
0.4% |
| Clinical Trial |
7 |
0.3% |
| Observational |
6 |
0.3% |
| Review |
557 |
23.6% |
| Case Report |
69 |
2.9% |
| Other |
1646 |
69.8% |
近期重要文獻
- Prognostic Biomarkers for Predicting Decompensation in Alcoholic and Nonalcoholic Patients With Compensated Cirrhosis: An Umbrella Review. — Biochemistry research international, 2026-01-01
- Respiratory oscillometry in monitoring lung transplant allograft function: a systematic scoping review. — European respiratory review : an official journal of the European Respiratory Society, 2026-01-01
- Therapeutic potential of MSCs and their exosomes in hepatic Ischaemia-Reperfusion injury: a systematic review and meta-analysis of rodent studies. — Stem cells translational medicine, 2026-01-26
- Histone Deacetylases as Epigenetic Regulators of EMT in Hypoxia-driven Tumor Metastasis: Mechanistic Insights and Therapeutic Implications. — Recent patents on anti-cancer drug discovery, 2026-01-16
- Genetic Association of Circulating Proteins and Gene Transcripts With Spontaneous Coronary Artery Dissection. — Circulation. Genomic and precision medicine, 2026-01-29
Level 2 證據（RCT）
- Effects of the DailyColors™ polyphenol supplement on serum proteome, cognitive function, and health in older adults at risk of cognitive and functional decline. — Food & function, 2025-06-03
- Mitochondria-Derived Vesicles and Inflammatory Profiles of Adults with Long COVID Supplemented with Red Beetroot Juice: Secondary Analysis of a Randomized Controlled Trial. — International journal of molecular sciences, 2025-01-30
- Novel Multi-Ingredient Supplement Facilitates Weight Loss and Improves Body Composition in Overweight and Obese Individuals: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. — Nutrients, 2023-08-23
- Inulin-induced differences on serum extracellular vesicles derived miRNAs in dairy cows suffering from subclinical mastitis. — Animal : an international journal of animal bioscience, 2023-09-01
- 功效分類：cardiovascular, immune, metabolic
- Circulating Metabolites Treat Human TMJ-OA by Eliminating Senescent Chondrocytes via the C1QBP/C1q/p14ARF Axis. — Journal of extracellular vesicles, 2026-02-01
- 功效分類：immune, musculoskeletal