乳酸桿菌文獻薈萃報告 — 2026 年 2 月
摘要
本月共收錄 乳酸桿菌 相關文獻 466 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）27 篇，RCT 3 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 27 | 5.8% |
| Level 2 (RCT) | 3 | 0.6% |
| Level 3 (Clinical Trial) | 3 | 0.6% |
| Level 4 (Observational) | 0 | 0.0% |
| Level 5 (Review/Case Report/Other) | 433 | 92.9% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| digestive | 消化 | 398 | 85.4% |
| immune | 免疫調節 | 209 | 44.8% |
| metabolic | 代謝 | 95 | 20.4% |
| cognitive | 認知功能 | 52 | 11.2% |
| cardiovascular | 心血管 | 49 | 10.5% |
| other | 其他 | 42 | 9.0% |
| anti_aging | 抗衰老 | 32 | 6.9% |
| musculoskeletal | 肌肉骨骼 | 31 | 6.7% |
| skin | 皮膚 | 18 | 3.9% |
| energy | 活力 | 16 | 3.4% |
| sexual | 性功能 | 8 | 1.7% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| probiotics | 204 |
| iron | 80 |
| EPA | 58 |
| prebiotics | 37 |
| fiber | 23 |
| NAC | 9 |
| calcium | 9 |
| vitamin D | 7 |
| omega-3 | 6 |
| collagen | 5 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| iron + probiotics | 46 |
| prebiotics + probiotics | 33 |
| EPA + probiotics | 28 |
| EPA + iron | 12 |
| fiber + probiotics | 11 |
| iron + prebiotics | 7 |
| fiber + iron | 7 |
| NAC + probiotics | 5 |
| omega-3 + probiotics | 5 |
| probiotics + vitamin D | 5 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 消化 | 免疫調節 | 代謝 | 心血管 | 肌肉骨骼 | 認知功能 |
|---|---|---|---|---|---|---|---|
| probiotics | 204 | 204 | 115 | 44 | 24 | 18 | 26 |
| iron | 80 | 71 | 47 | 10 | 6 | 6 | 8 |
| EPA | 58 | 47 | 32 | 11 | 6 | 7 | 2 |
| prebiotics | 37 | 37 | 26 | 14 | 8 | 4 | 9 |
| fiber | 23 | 22 | 11 | 6 | 8 | 3 | 1 |
| NAC | 9 | 8 | 5 | - | 1 | - | 1 |
| calcium | 9 | 7 | 4 | 4 | 1 | 6 | - |
| vitamin D | 7 | 6 | 4 | 3 | 1 | 4 | - |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 10 | 2.1% |
| Systematic Review | 17 | 3.6% |
| RCT | 3 | 0.6% |
| Clinical Trial | 3 | 0.6% |
| Observational | 0 | 0.0% |
| Review | 115 | 24.7% |
| Case Report | 2 | 0.4% |
| Other | 316 | 67.8% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- The association between gut microbiota and cognitive decline: A systematic review of the literature. — Nutrition research (New York, N.Y.), 2026-01-12
- 功效分類：cognitive, immune, digestive
- The role of short-chain fatty acids in spinal cord injury: A systematic review of human and animal evidence. — The journal of spinal cord medicine, 2026-02-19
- 功效分類：immune, digestive
- Bacterial Diversity of Deep Carious Lesions Analysed by Next-Generation Sequencing Approaches Associated With Different Pulp Diagnoses: A Systematic Review. — International endodontic journal, 2026-02-12
- 功效分類：digestive
- Microbial dysbiosis as a diagnostic marker in psychiatric disorders: a systematic review of gut-brain axis disruptions. — Frontiers in neuroscience, 2026-01-01
- 功效分類：cognitive, digestive
- The Interplay Between Ketogenic Diet and the Microbiota-Gut-Brain Axis in Drug-Resistant Epilepsy: A Systematic Review. — Nutrition reviews, 2026-02-10
- 功效分類：cognitive, immune, metabolic, digestive
Level 2 證據（RCT）
- Novel Therapeutic Approaches for Treating Moderate-to-Severe Atopic Dermatitis in Infants with Polyvalent Allergic Sensitisation. — Journal of mother and child, 2026-01-01
- 功效分類：immune, digestive
- Impact of Subgingival Lactobacillus reuteri Probiotic Therapy on Clinical Outcomes and Porphyromonas gingivalis Quantification in Peri-Implant Disease: A Prospective RT-PCR-Based Clinical Study. — Journal of long-term effects of medical implants, 2026-01-01
- 功效分類：immune, digestive
- Therapeutic Impact of Systemic Probiotics Combined with Mechanical Debridement in Peri-Implant Disease: A Clinical and Microbiological Evaluation. — Journal of long-term effects of medical implants, 2026-01-01
- 功效分類：anti_aging, immune, digestive
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