乳酸桿菌文獻薈萃報告 — 2026 年 3 月
摘要
本月共收錄 乳酸桿菌 相關文獻 1167 篇,其中 Level 1 證據(Meta-Analysis/Systematic Review)80 篇,RCT 7 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 80 | 6.9% |
| Level 2 (RCT) | 7 | 0.6% |
| Level 3 (Clinical Trial) | 6 | 0.5% |
| Level 4 (Observational) | 0 | 0.0% |
| Level 5 (Review/Case Report/Other) | 1074 | 92.0% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| digestive | 消化 | 982 | 84.1% |
| immune | 免疫調節 | 515 | 44.1% |
| metabolic | 代謝 | 281 | 24.1% |
| cardiovascular | 心血管 | 130 | 11.1% |
| cognitive | 認知功能 | 128 | 11.0% |
| other | 其他 | 114 | 9.8% |
| anti_aging | 抗衰老 | 87 | 7.5% |
| musculoskeletal | 肌肉骨骼 | 63 | 5.4% |
| skin | 皮膚 | 46 | 3.9% |
| energy | 活力 | 36 | 3.1% |
| sexual | 性功能 | 20 | 1.7% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| probiotics | 488 |
| iron | 169 |
| EPA | 152 |
| prebiotics | 97 |
| fiber | 54 |
| NAC | 24 |
| calcium | 20 |
| vitamin D | 11 |
| omega-3 | 10 |
| zinc | 10 |
成分組合分析
以下列出最常被共同研究的成分組合:
| 成分組合 | 共同出現文獻數 |
|---|---|
| prebiotics + probiotics | 92 |
| iron + probiotics | 89 |
| EPA + probiotics | 69 |
| fiber + probiotics | 28 |
| EPA + iron | 23 |
| iron + prebiotics | 18 |
| NAC + probiotics | 12 |
| fiber + prebiotics | 11 |
| calcium + probiotics | 11 |
| EPA + prebiotics | 10 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數:
| 成分 | 總文獻 | 消化 | 免疫調節 | 代謝 | 心血管 | 認知功能 | 抗衰老 |
|---|---|---|---|---|---|---|---|
| probiotics | 488 | 488 | 282 | 118 | 64 | 68 | 57 |
| iron | 169 | 149 | 96 | 33 | 14 | 12 | 12 |
| EPA | 152 | 131 | 87 | 55 | 29 | 12 | 20 |
| prebiotics | 97 | 97 | 73 | 30 | 18 | 22 | 17 |
| fiber | 54 | 52 | 27 | 16 | 19 | 4 | 7 |
| NAC | 24 | 22 | 15 | 2 | 1 | 3 | 2 |
| calcium | 20 | 15 | 10 | 7 | 4 | 2 | 1 |
| vitamin D | 11 | 10 | 6 | 4 | 1 | - | - |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 36 | 3.1% |
| Systematic Review | 44 | 3.8% |
| RCT | 7 | 0.6% |
| Clinical Trial | 6 | 0.5% |
| Observational | 0 | 0.0% |
| Review | 273 | 23.4% |
| Case Report | 2 | 0.2% |
| Other | 799 | 68.5% |
近期重要文獻
Level 1 證據(Meta-Analysis / Systematic Review)
- [Therapeutic Strategies in the Management of Functional Constipation in Children: A narrative review]. — Andes pediatrica : revista Chilena de pediatria, 2025-12-01
- 功效分類:digestive
- The association between gut microbiota and cognitive decline: A systematic review of the literature. — Nutrition research (New York, N.Y.), 2026-01-12
- 功效分類:cognitive, immune, digestive
- An Umbrella Review on the Prevention of Skin Diseases: Do Specific Nutrients Play a Protective Role? — Preventive nutrition and food science, 2026-02-01
- 功效分類:skin
- The role of short-chain fatty acids in spinal cord injury: A systematic review of human and animal evidence. — The journal of spinal cord medicine, 2026-02-19
- 功效分類:immune, digestive
- Probiotics for Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis With Trial Sequential Analysis. — Journal of gastroenterology and hepatology, 2026-03-12
- 功效分類:digestive
Level 2 證據(RCT)
- Multi-strain probiotic reduces gastrointestinal side effects in women with elevated HOMA-IR index treated with metformin: a 12-week randomised controlled trial. — Frontiers in endocrinology, 2026-01-01
- 功效分類:cardiovascular, metabolic, digestive
- Novel Therapeutic Approaches for Treating Moderate-to-Severe Atopic Dermatitis in Infants with Polyvalent Allergic Sensitisation. — Journal of mother and child, 2026-01-01
- 功效分類:immune, digestive
- Impact of Subgingival Lactobacillus reuteri Probiotic Therapy on Clinical Outcomes and Porphyromonas gingivalis Quantification in Peri-Implant Disease: A Prospective RT-PCR-Based Clinical Study. — Journal of long-term effects of medical implants, 2026-01-01
- 功效分類:immune, digestive
- Therapeutic Impact of Systemic Probiotics Combined with Mechanical Debridement in Peri-Implant Disease: A Clinical and Microbiological Evaluation. — Journal of long-term effects of medical implants, 2026-01-01
- 功效分類:anti_aging, immune, digestive
- Effect of — International journal of medical sciences, 2026-01-01
- 功效分類:cognitive, digestive
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