乳酸桿菌文獻薈萃報告 — 2026 年 3 月

摘要

本月共收錄 乳酸桿菌 相關文獻 1167 篇,其中 Level 1 證據(Meta-Analysis/Systematic Review)80 篇,RCT 7 篇。

證據等級分布

證據等級 文獻數 佔比
Level 1 (Meta-Analysis/Systematic Review) 80 6.9%
Level 2 (RCT) 7 0.6%
Level 3 (Clinical Trial) 6 0.5%
Level 4 (Observational) 0 0.0%
Level 5 (Review/Case Report/Other) 1074 92.0%

功效分類統計

功效分類 中文 文獻數 佔比
digestive 消化 982 84.1%
immune 免疫調節 515 44.1%
metabolic 代謝 281 24.1%
cardiovascular 心血管 130 11.1%
cognitive 認知功能 128 11.0%
other 其他 114 9.8%
anti_aging 抗衰老 87 7.5%
musculoskeletal 肌肉骨骼 63 5.4%
skin 皮膚 46 3.9%
energy 活力 36 3.1%
sexual 性功能 20 1.7%

成分搭配統計

成分 文獻數
probiotics 488
iron 169
EPA 152
prebiotics 97
fiber 54
NAC 24
calcium 20
vitamin D 11
omega-3 10
zinc 10

成分組合分析

以下列出最常被共同研究的成分組合:

成分組合 共同出現文獻數
prebiotics + probiotics 92
iron + probiotics 89
EPA + probiotics 69
fiber + probiotics 28
EPA + iron 23
iron + prebiotics 18
NAC + probiotics 12
fiber + prebiotics 11
calcium + probiotics 11
EPA + prebiotics 10

成分功效分析

以下列出主要成分在各功效領域的研究文獻數:

成分 總文獻 消化 免疫調節 代謝 心血管 認知功能 抗衰老
probiotics 488 488 282 118 64 68 57
iron 169 149 96 33 14 12 12
EPA 152 131 87 55 29 12 20
prebiotics 97 97 73 30 18 22 17
fiber 54 52 27 16 19 4 7
NAC 24 22 15 2 1 3 2
calcium 20 15 10 7 4 2 1
vitamin D 11 10 6 4 1 - -

研究類型分布

研究類型 文獻數 佔比
Meta-Analysis 36 3.1%
Systematic Review 44 3.8%
RCT 7 0.6%
Clinical Trial 6 0.5%
Observational 0 0.0%
Review 273 23.4%
Case Report 2 0.2%
Other 799 68.5%

近期重要文獻

Level 1 證據(Meta-Analysis / Systematic Review)

  1. [Therapeutic Strategies in the Management of Functional Constipation in Children: A narrative review]. — Andes pediatrica : revista Chilena de pediatria, 2025-12-01
    • 功效分類:digestive
  2. The association between gut microbiota and cognitive decline: A systematic review of the literature. — Nutrition research (New York, N.Y.), 2026-01-12
    • 功效分類:cognitive, immune, digestive
  3. An Umbrella Review on the Prevention of Skin Diseases: Do Specific Nutrients Play a Protective Role? — Preventive nutrition and food science, 2026-02-01
    • 功效分類:skin
  4. The role of short-chain fatty acids in spinal cord injury: A systematic review of human and animal evidence. — The journal of spinal cord medicine, 2026-02-19
    • 功效分類:immune, digestive
  5. Probiotics for Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis With Trial Sequential Analysis. — Journal of gastroenterology and hepatology, 2026-03-12
    • 功效分類:digestive

Level 2 證據(RCT)

  1. Multi-strain probiotic reduces gastrointestinal side effects in women with elevated HOMA-IR index treated with metformin: a 12-week randomised controlled trial. — Frontiers in endocrinology, 2026-01-01
    • 功效分類:cardiovascular, metabolic, digestive
  2. Novel Therapeutic Approaches for Treating Moderate-to-Severe Atopic Dermatitis in Infants with Polyvalent Allergic Sensitisation. — Journal of mother and child, 2026-01-01
    • 功效分類:immune, digestive
  3. Impact of Subgingival Lactobacillus reuteri Probiotic Therapy on Clinical Outcomes and Porphyromonas gingivalis Quantification in Peri-Implant Disease: A Prospective RT-PCR-Based Clinical Study. — Journal of long-term effects of medical implants, 2026-01-01
    • 功效分類:immune, digestive
  4. Therapeutic Impact of Systemic Probiotics Combined with Mechanical Debridement in Peri-Implant Disease: A Clinical and Microbiological Evaluation. — Journal of long-term effects of medical implants, 2026-01-01
    • 功效分類:anti_aging, immune, digestive
  5. Effect of — International journal of medical sciences, 2026-01-01
    • 功效分類:cognitive, digestive

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