葉黃素文獻薈萃報告 — 2026 年 6 月
摘要
本月共收錄 葉黃素 相關文獻 1263 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）44 篇，RCT 22 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 44 | 3.5% |
| Level 2 (RCT) | 22 | 1.7% |
| Level 3 (Clinical Trial) | 7 | 0.6% |
| Level 4 (Observational) | 4 | 0.3% |
| Level 5 (Review/Case Report/Other) | 1186 | 93.9% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| other | 其他 | 641 | 50.8% |
| cardiovascular | 心血管 | 181 | 14.3% |
| immune | 免疫調節 | 160 | 12.7% |
| metabolic | 代謝 | 142 | 11.2% |
| cognitive | 認知功能 | 112 | 8.9% |
| anti_aging | 抗衰老 | 112 | 8.9% |
| digestive | 消化 | 71 | 5.6% |
| energy | 活力 | 70 | 5.5% |
| skin | 皮膚 | 53 | 4.2% |
| musculoskeletal | 肌肉骨骼 | 35 | 2.8% |
| sexual | 性功能 | 22 | 1.7% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| lutein | 717 |
| zeaxanthin | 424 |
| iron | 115 |
| EPA | 102 |
| astaxanthin | 57 |
| vitamin A | 44 |
| NAC | 37 |
| vitamin E | 29 |
| omega-3 | 25 |
| zinc | 24 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| lutein + zeaxanthin | 278 |
| EPA + lutein | 78 |
| iron + lutein | 72 |
| iron + zeaxanthin | 40 |
| astaxanthin + lutein | 37 |
| EPA + zeaxanthin | 34 |
| lutein + vitamin A | 32 |
| astaxanthin + zeaxanthin | 28 |
| vitamin A + zeaxanthin | 26 |
| lutein + vitamin E | 24 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 其他 | 心血管 | 免疫調節 | 代謝 | 認知功能 | 抗衰老 |
|---|---|---|---|---|---|---|---|
| lutein | 717 | 318 | 134 | 112 | 88 | 88 | 69 |
| zeaxanthin | 424 | 188 | 76 | 57 | 65 | 50 | 32 |
| iron | 115 | 60 | 13 | 16 | 9 | 6 | 8 |
| EPA | 102 | 38 | 23 | 14 | 16 | 7 | 9 |
| astaxanthin | 57 | 26 | 16 | 14 | 10 | 7 | 4 |
| vitamin A | 44 | 17 | 10 | 8 | 8 | 6 | 4 |
| NAC | 37 | 20 | 7 | 3 | 10 | 2 | 1 |
| vitamin E | 29 | 10 | 5 | 5 | 4 | 3 | 2 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 21 | 1.7% |
| Systematic Review | 23 | 1.8% |
| RCT | 22 | 1.7% |
| Clinical Trial | 7 | 0.6% |
| Observational | 4 | 0.3% |
| Review | 50 | 4.0% |
| Case Report | 10 | 0.8% |
| Other | 1126 | 89.2% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Lutein-fortified infant formula for newborn health: a comprehensive patent review and a systematic review of clinical trials. — Critical reviews in food science and nutrition, 2026-06-05
- 功效分類：cognitive
- Not all carotenoids can reduce the risk of gastric cancer: a systematic review with meta-analysis. — BMC gastroenterology,
- 功效分類：other
- The neuropharmacological and clinical effects of lutein: a systematic review. — Hormone molecular biology and clinical investigation,
- 功效分類：cognitive
- The differential effects of lutein and zeaxanthin supplementation on myopia prevention in adolescents: a systematic review and Meta-analysis. — International journal of ophthalmology,
- 功效分類：other
- A Systematic Review of Carotenoids in the Management of Diabetic Retinopathy. — Nutrients, 2021-07-16
- 功效分類：cognitive, immune, metabolic
Level 2 證據（RCT）
- Supplementation With Carotenoids, Omega-3 Fatty Acids, and Vitamin E Has a Positive Effect on the Symptoms and Progression of Alzheimer’s Disease. — Journal of Alzheimer’s disease : JAD, 2022-01-01
- 功效分類：cognitive, skin
- Night Vision and Carotenoids (NVC): A Randomized Placebo Controlled Clinical Trial on Effects of Carotenoid Supplementation on Night Vision in Older Adults. — Nutrients, 2021-09-14
- 功效分類：other
- A Randomized Study of Nutritional Supplementation in Patients with Unilateral Wet Age-Related Macular Degeneration. — Nutrients, 2021-04-10
- 功效分類：other
- Efficacy of lutein supplements on macular pigment optical density in highly myopic individuals: A randomized controlled trial. — Medicine, 2023-03-24
- 功效分類：other
- Effects of lutein on jejunal mucosal barrier function and inflammatory responses in lipopolysaccharide-challenged yellow-feather broilers. — Poultry science, 2022-12-01
- 功效分類：immune, metabolic, digestive
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