菸鹼酸文獻薈萃報告 — 2026 年 3 月
摘要
本月共收錄 菸鹼酸 相關文獻 549 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）9 篇，RCT 6 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 9 | 1.6% |
| Level 2 (RCT) | 6 | 1.1% |
| Level 3 (Clinical Trial) | 3 | 0.5% |
| Level 4 (Observational) | 3 | 0.5% |
| Level 5 (Review/Case Report/Other) | 528 | 96.2% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| other | 其他 | 267 | 48.6% |
| metabolic | 代謝 | 85 | 15.5% |
| immune | 免疫調節 | 80 | 14.6% |
| cardiovascular | 心血管 | 79 | 14.4% |
| anti_aging | 抗衰老 | 66 | 12.0% |
| cognitive | 認知功能 | 45 | 8.2% |
| energy | 活力 | 41 | 7.5% |
| musculoskeletal | 肌肉骨骼 | 36 | 6.6% |
| digestive | 消化 | 34 | 6.2% |
| skin | 皮膚 | 20 | 3.6% |
| sexual | 性功能 | 8 | 1.5% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| EPA | 72 |
| iron | 49 |
| calcium | 27 |
| vitamin C | 21 |
| fiber | 21 |
| folate | 20 |
| NAC | 19 |
| vitamin A | 18 |
| vitamin D | 15 |
| vitamin B12 | 15 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| calcium + iron | 14 |
| iron + vitamin C | 12 |
| calcium + magnesium | 11 |
| calcium + vitamin C | 11 |
| calcium + fiber | 10 |
| folate + iron | 9 |
| iron + magnesium | 9 |
| iron + zinc | 9 |
| calcium + vitamin A | 8 |
| fiber + magnesium | 8 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 其他 | 心血管 | 代謝 | 活力 | 免疫調節 | 抗衰老 |
|---|---|---|---|---|---|---|---|
| EPA | 72 | 35 | 8 | 11 | 5 | 12 | 9 |
| iron | 49 | 18 | 11 | 13 | 8 | 9 | 2 |
| calcium | 27 | 10 | 7 | 5 | 8 | 2 | 1 |
| vitamin C | 21 | 7 | 7 | 5 | 7 | 2 | 2 |
| fiber | 21 | 7 | 5 | 3 | 5 | 4 | 3 |
| folate | 20 | 5 | 6 | 7 | 5 | 5 | 2 |
| NAC | 19 | 6 | 7 | 2 | 2 | 5 | 3 |
| vitamin A | 18 | 3 | 7 | 4 | 7 | 4 | 1 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 4 | 0.7% |
| Systematic Review | 5 | 0.9% |
| RCT | 6 | 1.1% |
| Clinical Trial | 3 | 0.5% |
| Observational | 3 | 0.5% |
| Review | 28 | 5.1% |
| Case Report | 13 | 2.4% |
| Other | 487 | 88.7% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Intact Posterior Tension Band in Spinal Fractures in Patients With Spinal Ankylosing Disorders - Is it a Myth or a Reality? A Systematic Review. — Global spine journal, 2026-01-29
- 功效分類：other
- Optimal analgesia after laparoscopic total hysterectomy with pre-pneumoperitoneum phrenic nerve block using different ropivacaine concentrations: randomized controlled trial. — BMC anesthesiology, 2025-10-27
- 功效分類：other
- NAD⁺ supplementation for anti-aging and wellness: a PRISMA-guided systematic review of preclinical and clinical evidence. — Ageing research reviews, 2026-02-06
- 功效分類：anti_aging, immune
- Pellagra in Contemporary Clinical Practice (2000-2023): A Systematic Review. — International journal of dermatology, 2026-03-24
- 功效分類：cognitive, digestive
- Potential role of breast MRI to identify patients with high-risk lesions who might avoid surgery: a systematic review and meta-analysis. — European radiology, 2026-01-17
- 功效分類：anti_aging
Level 2 證據（RCT）
- Nixtamalization of Maize to Reduce Mycotoxin Exposure: A Human Biomonitoring Intervention Study in Soweto, South Africa. — Toxins, 2025-10-26
- 功效分類：other
- Effects of Different Doses of Butorphanol on Perioperative Analgesia, Recovery, and Immune Function in Patients Undergoing Cytoreductive Surgery for Ovarian Cancer: A Randomized Controlled Trial. — Drug design, development and therapy, 2025-01-01
- 功效分類：immune
- The differential impact of three different NAD — Nature metabolism, 2026-01-01
- 功效分類：other
- Isolating the effects of carbohydrate and lipid availability on exercise-induced skeletal muscle signalling in males. — The Journal of physiology, 2026-01-01
- 功效分類：cardiovascular, musculoskeletal
- Improved HDL, LDL and total cholesterol levels following a 3-month administration of Mentha spicata leaf extract and Amaranthus caudatus seed flour extracts, flavonoids and B vitamins. A placebo-controlled, double-blind, randomized clinical trial. — Nutrition, metabolism, and cardiovascular diseases : NMCD, 2026-03-01
- 功效分類：cardiovascular
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