紅麴文獻薈萃報告 — 2026 年 6 月
摘要
本月共收錄 紅麴 相關文獻 186 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）12 篇，RCT 11 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 12 | 6.5% |
| Level 2 (RCT) | 11 | 5.9% |
| Level 3 (Clinical Trial) | 2 | 1.1% |
| Level 4 (Observational) | 1 | 0.5% |
| Level 5 (Review/Case Report/Other) | 160 | 86.0% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| cardiovascular | 心血管 | 167 | 89.8% |
| metabolic | 代謝 | 49 | 26.3% |
| immune | 免疫調節 | 22 | 11.8% |
| other | 其他 | 16 | 8.6% |
| digestive | 消化 | 16 | 8.6% |
| musculoskeletal | 肌肉骨骼 | 14 | 7.5% |
| anti_aging | 抗衰老 | 9 | 4.8% |
| energy | 活力 | 4 | 2.2% |
| cognitive | 認知功能 | 2 | 1.1% |
| sexual | 性功能 | 1 | 0.5% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| NAC | 72 |
| EPA | 38 |
| berberine | 18 |
| garlic | 8 |
| coenzyme Q10 | 5 |
| fiber | 5 |
| creatine | 4 |
| omega-3 | 4 |
| astaxanthin | 3 |
| glutathione | 3 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| EPA + NAC | 19 |
| NAC + berberine | 6 |
| berberine + garlic | 5 |
| berberine + fiber | 4 |
| NAC + glutathione | 3 |
| NAC + coenzyme Q10 | 3 |
| fiber + garlic | 3 |
| berberine + green tea | 3 |
| garlic + green tea | 3 |
| cinnamon + garlic | 3 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 心血管 | 代謝 | 免疫調節 | 消化 | 肌肉骨骼 | 抗衰老 |
|---|---|---|---|---|---|---|---|
| NAC | 72 | 66 | 9 | 9 | 5 | 6 | 3 |
| EPA | 38 | 38 | 14 | 7 | 5 | 4 | 2 |
| berberine | 18 | 18 | 6 | - | 2 | 2 | 1 |
| garlic | 8 | 8 | 1 | 1 | 1 | 1 | 1 |
| coenzyme Q10 | 5 | 4 | 1 | 1 | - | - | - |
| fiber | 5 | 5 | 1 | - | 2 | - | 1 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 10 | 5.4% |
| Systematic Review | 2 | 1.1% |
| RCT | 11 | 5.9% |
| Clinical Trial | 2 | 1.1% |
| Observational | 1 | 0.5% |
| Review | 28 | 15.1% |
| Case Report | 11 | 5.9% |
| Other | 121 | 65.1% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Effectiveness of red yeast rice on carotid atherosclerosis: A systematic review and meta-analysis. — Frontiers in pharmacology, 2022-01-01
- 功效分類：cardiovascular
- Effects of the combination of red yeast rice-containing commercial Chinese polyherbal preparation with statins for dyslipidemia: a systematic review and meta-analysis. — Frontiers in pharmacology, 2024-01-01
- 功效分類：cardiovascular
- A network meta-analysis on the comparative effect of nutraceuticals on lipid profile in adults. — Pharmacological research, 2022-09-01
- 功效分類：cardiovascular, musculoskeletal
- Comparing the effectiveness of Chinese patent medicines containing red yeast rice on hyperlipidaemia: A network meta-analysis of randomized controlled trials. — Endocrinology, diabetes & metabolism, 2022-01-01
- 功效分類：cardiovascular
- Monacolin K supplementation in patients with hypercholesterolemia: A systematic review of clinical trials. — Semergen, 2024-01-01
- 功效分類：cardiovascular
Level 2 證據（RCT）
- Efficacy of AI-Guided (GenAIS — Nutrients, 2024-06-26
- 功效分類：cardiovascular, metabolic
- Dual modulation of lipid and glucose metabolism by a nutraceutical combination in patients at cardiometabolic risk: results from a multicenter randomized controlled trial. — Cardiovascular diabetology, 2025-10-03
- 功效分類：cardiovascular, metabolic
- Low dose red yeast rice with monacolin K lowers LDL cholesterol and blood pressure in Japanese with mild dyslipidemia: A multicenter, randomized trial. — Asia Pacific journal of clinical nutrition, 2021-09-01
- 功效分類：cardiovascular, musculoskeletal
- Efficacy of Food Supplement Based on Monacolins, γ-Oryzanol, and γ-Aminobutyric Acid in Mild Dyslipidemia: A Randomized, Double-Blind, Parallel-Armed, Placebo-Controlled Clinical Trial. — Nutrients, 2024-09-04
- 功效分類：cardiovascular
- Randomized, Double-Blind, Placebo-Controlled Trial to Test the Effects of a Nutraceutical Combination Monacolin K-Free on the Lipid and Inflammatory Profile of Subjects with Hypercholesterolemia. — Nutrients, 2022-07-08
- 功效分類：cardiovascular, immune
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