Vitamin A文獻薈萃報告 — 2026 年 4 月

摘要

本月共收錄 Vitamin A 相關文獻 589 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）27 篇，RCT 13 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	27	4.6%
Level 2 (RCT)	13	2.2%
Level 3 (Clinical Trial)	0	0.0%
Level 4 (Observational)	6	1.0%
Level 5 (Review/Case Report/Other)	543	92.2%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	277	47.0%
immune	免疫調節	105	17.8%
metabolic	代謝	90	15.3%
cardiovascular	心血管	70	11.9%
energy	活力	42	7.1%
anti_aging	抗衰老	40	6.8%
musculoskeletal	肌肉骨骼	40	6.8%
digestive	消化	39	6.6%
cognitive	認知功能	39	6.6%
skin	皮膚	34	5.8%
sexual	性功能	12	2.0%

成分搭配統計

成分	文獻數
vitamin A	511
iron	116
vitamin D	82
zinc	78
EPA	73
vitamin E	65
vitamin C	58
calcium	53
folate	41
selenium	36

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
iron + vitamin A	110
vitamin A + vitamin D	76
vitamin A + zinc	73
EPA + vitamin A	63
vitamin A + vitamin E	61
vitamin A + vitamin C	56
iron + zinc	53
calcium + vitamin A	52
folate + vitamin A	38
folate + iron	36

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	免疫調節	代謝	心血管	活力	認知功能
vitamin A	511	243	90	82	61	36	37
iron	116	44	24	19	14	19	9
vitamin D	82	39	15	14	10	7	9
zinc	78	22	18	16	9	15	8
EPA	73	32	19	17	11	4	1
vitamin E	65	31	10	14	7	7	4
vitamin C	58	21	12	12	8	11	3
calcium	53	15	8	10	10	17	3

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	15	2.5%
Systematic Review	12	2.0%
RCT	13	2.2%
Clinical Trial	0	0.0%
Observational	6	1.0%
Review	52	8.8%
Case Report	14	2.4%
Other	477	81.0%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. Systematic Review of Nutrients’ Impact on Cognition and School Performance in School-Aged Children in Sub-Saharan Africa. — Nutrition reviews, 2026-03-13
   • 功效分類：cardiovascular, cognitive
2. Additional treatment strategies for Hypothyroidism: A Network Meta-Analysis. — Endocrine connections, 2026-03-13
   • 功效分類：other
3. The Effects of Salt Fortified with Multiple Nutrients on Health Outcomes in Children, Adolescents, and Adults: A Systematic Review and Meta-Analysis. — Advances in nutrition (Bethesda, Md.), 2026-01-01
   • 功效分類：other
4. The Efficacy of Oral Vitamin Supplementation in Dry Eye Disease: A Systematic Review. — Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026-04-15
   • 功效分類：immune
5. The influence of nutrition on HPV-associated inflammation: a systematic review and meta-analysis. — Frontiers in nutrition, 2025-01-01
   • 功效分類：immune

Level 2 證據（RCT）

1. Serum Vitamin A Is Associated with Variations in the Relationship between Plasma B6 Vitamers and Cardiovascular Disease Risk. — The Journal of nutrition, 2026-01-01
   • 功效分類：cardiovascular
2. Red palm olein biscuit supplementation modulates gut microbiota in vitamin A deficient rural Malaysian schoolchildren: a randomised controlled trial. — Nature communications, 2025-10-22
   • 功效分類：digestive
3. Associations between dietary patterns and adequate intake of climate-sensitive micronutrients among young children living in Siaya County, Kenya: Findings from the ALIMUS study baseline data. — Journal of health, population, and nutrition, 2026-03-26
   • 功效分類：other
4. Women-led sustainable irrigation improved indicators of nutritional status in children from Northern Benin. — Journal of health, population, and nutrition, 2025-12-08
   • 功效分類：other
5. Perception and acceptance of micronutrient-Fortified Bouillon among Non-Index Household Members: A longitudinal sub-study nested within a randomized trial in Northern Ghana. — PloS one, 2026-01-01
   • 功效分類：sexual

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