Vitamin A文獻薈萃報告 — 2026 年 6 月

摘要

本月共收錄 Vitamin A 相關文獻 717 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）37 篇，RCT 14 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	37	5.2%
Level 2 (RCT)	14	2.0%
Level 3 (Clinical Trial)	0	0.0%
Level 4 (Observational)	8	1.1%
Level 5 (Review/Case Report/Other)	658	91.8%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	328	45.7%
immune	免疫調節	135	18.8%
metabolic	代謝	121	16.9%
cardiovascular	心血管	85	11.9%
energy	活力	55	7.7%
digestive	消化	51	7.1%
musculoskeletal	肌肉骨骼	48	6.7%
anti_aging	抗衰老	48	6.7%
cognitive	認知功能	46	6.4%
skin	皮膚	38	5.3%
sexual	性功能	16	2.2%

成分搭配統計

成分	文獻數
vitamin A	620
iron	142
vitamin D	108
zinc	96
EPA	93
vitamin E	83
vitamin C	68
calcium	59
folate	52
selenium	46

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
iron + vitamin A	134
vitamin A + vitamin D	100
vitamin A + zinc	91
EPA + vitamin A	81
vitamin A + vitamin E	79
vitamin A + vitamin C	66
iron + zinc	62
calcium + vitamin A	58
folate + vitamin A	48
vitamin D + vitamin E	43

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	免疫調節	代謝	心血管	活力	認知功能
vitamin A	620	285	117	109	74	46	43
iron	142	53	32	25	17	22	11
vitamin D	108	48	20	22	12	7	11
zinc	96	25	23	23	10	20	11
EPA	93	36	25	25	14	6	3
vitamin E	83	36	16	21	9	10	6
vitamin C	68	24	14	15	9	13	5
calcium	59	16	10	11	11	19	5

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	18	2.5%
Systematic Review	19	2.6%
RCT	14	2.0%
Clinical Trial	0	0.0%
Observational	8	1.1%
Review	63	8.8%
Case Report	16	2.2%
Other	579	80.8%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. Systematic Review of Nutrients’ Impact on Cognition and School Performance in School-Aged Children in Sub-Saharan Africa. — Nutrition reviews, 2026-03-13
   • 功效分類：cardiovascular, cognitive
2. Additional treatment strategies for Hypothyroidism: A Network Meta-Analysis. — Endocrine connections, 2026-03-13
   • 功效分類：other
3. The Effects of Salt Fortified with Multiple Nutrients on Health Outcomes in Children, Adolescents, and Adults: A Systematic Review and Meta-Analysis. — Advances in nutrition (Bethesda, Md.), 2026-01-01
   • 功效分類：other
4. Clinical Spectrum and Management of Hypervitaminosis A: A Systematic Review of Case-Based Evidence. — Clinica chimica acta; international journal of clinical chemistry, 2026-05-22
   • 功效分類：cognitive, musculoskeletal, skin, digestive
5. The Efficacy of Oral Vitamin Supplementation in Dry Eye Disease: A Systematic Review. — Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists), 2026-04-15
   • 功效分類：immune

Level 2 證據（RCT）

1. Serum Vitamin A Is Associated with Variations in the Relationship between Plasma B6 Vitamers and Cardiovascular Disease Risk. — The Journal of nutrition, 2026-01-01
   • 功效分類：cardiovascular
2. Red palm olein biscuit supplementation modulates gut microbiota in vitamin A deficient rural Malaysian schoolchildren: a randomised controlled trial. — Nature communications, 2025-10-22
   • 功效分類：digestive
3. Associations between dietary patterns and adequate intake of climate-sensitive micronutrients among young children living in Siaya County, Kenya: Findings from the ALIMUS study baseline data. — Journal of health, population, and nutrition, 2026-03-26
   • 功效分類：other
4. Women-led sustainable irrigation improved indicators of nutritional status in children from Northern Benin. — Journal of health, population, and nutrition, 2025-12-08
   • 功效分類：other
5. Comparison of mediterranean and healthy eating guideline interventions on the dietary inflammatory index in rheumatoid arthritis: results from a dietary randomised controlled intervention trial. — European journal of nutrition, 2026-05-26
   • 功效分類：immune, musculoskeletal, energy

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