維生素B6文獻薈萃報告 — 2026 年 2 月
摘要
本月共收錄 維生素B6 相關文獻 484 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）14 篇，RCT 6 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 14 | 2.9% |
| Level 2 (RCT) | 6 | 1.2% |
| Level 3 (Clinical Trial) | 2 | 0.4% |
| Level 4 (Observational) | 3 | 0.6% |
| Level 5 (Review/Case Report/Other) | 459 | 94.8% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| other | 其他 | 197 | 40.7% |
| metabolic | 代謝 | 121 | 25.0% |
| immune | 免疫調節 | 84 | 17.4% |
| cardiovascular | 心血管 | 72 | 14.9% |
| cognitive | 認知功能 | 48 | 9.9% |
| musculoskeletal | 肌肉骨骼 | 48 | 9.9% |
| digestive | 消化 | 39 | 8.1% |
| anti_aging | 抗衰老 | 38 | 7.9% |
| energy | 活力 | 34 | 7.0% |
| skin | 皮膚 | 14 | 2.9% |
| sexual | 性功能 | 6 | 1.2% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| vitamin B6 | 110 |
| iron | 73 |
| EPA | 62 |
| folate | 56 |
| vitamin B12 | 42 |
| calcium | 31 |
| magnesium | 30 |
| vitamin D | 29 |
| vitamin C | 27 |
| zinc | 26 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| vitamin B12 + vitamin B6 | 32 |
| folate + vitamin B6 | 28 |
| iron + vitamin B6 | 26 |
| calcium + iron | 23 |
| iron + magnesium | 23 |
| folate + vitamin B12 | 23 |
| iron + zinc | 22 |
| folate + iron | 21 |
| calcium + magnesium | 19 |
| calcium + zinc | 19 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 代謝 | 其他 | 免疫調節 | 心血管 | 活力 | 肌肉骨骼 |
|---|---|---|---|---|---|---|---|
| vitamin B6 | 110 | 47 | 33 | 18 | 26 | 7 | 11 |
| iron | 73 | 26 | 19 | 18 | 13 | 13 | 8 |
| EPA | 62 | 12 | 21 | 19 | 8 | 2 | 5 |
| folate | 56 | 20 | 21 | 11 | 13 | 6 | 5 |
| vitamin B12 | 42 | 13 | 14 | 8 | 8 | 5 | 6 |
| calcium | 31 | 7 | 11 | 2 | 4 | 8 | 5 |
| magnesium | 30 | 9 | 10 | 6 | 5 | 6 | 3 |
| vitamin D | 29 | 14 | 6 | 10 | 10 | 4 | 8 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 7 | 1.4% |
| Systematic Review | 7 | 1.4% |
| RCT | 6 | 1.2% |
| Clinical Trial | 2 | 0.4% |
| Observational | 3 | 0.6% |
| Review | 32 | 6.6% |
| Case Report | 18 | 3.7% |
| Other | 409 | 84.5% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis. — Annals of medicine, 2026-12-01
- 功效分類：cardiovascular, metabolic
- Branched-chain amino acid transferase 2 (BCAT2) deficiency: A case series and systematic review. — Molecular genetics and metabolism reports, 2026-03-01
- 功效分類：anti_aging, cognitive, metabolic
- Efficacy of B Vitamin Supplementation on Global Cognitive Function in Older Adults: A Systematic Review and Meta-analysis. — Nutrition reviews, 2025-12-01
- 功效分類：cognitive
- Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. — Frontiers in nutrition, 2025-01-01
- 功效分類：metabolic
- Acute non-alcoholic nutritional neuropathies in high-income countries - a systematic review. — Danish medical journal, 2025-10-21
- 功效分類：metabolic
Level 2 證據（RCT）
- Serum Vitamin A Is Associated with Variations in the Relationship between Plasma B6 Vitamers and Cardiovascular Disease Risk. — The Journal of nutrition, 2026-01-01
- 功效分類：cardiovascular
- Impact of sustainable diets on micronutrient intakes and status: outcomes of the MyPlanetDiet randomized controlled trial. — The American journal of clinical nutrition, 2025-11-01
- 功效分類：energy
- Metabolomic characteristics of aqueous humor in young myopia patients without fundus complications. — Eye (London, England), 2026-02-01
- 功效分類：cardiovascular, metabolic
- Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study. — Scientific reports, 2025-11-28
- 功效分類：other
- Antioxidant Treatment and the Chance to Conceive in Men Seeking Fertility Care: The SUMMER Randomized Clinical Trial. — JAMA network open, 2025-09-02
- 功效分類：anti_aging, sexual
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