維生素B6文獻薈萃報告 — 2026 年 4 月
摘要
本月共收錄 維生素B6 相關文獻 652 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）18 篇，RCT 6 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 18 | 2.8% |
| Level 2 (RCT) | 6 | 0.9% |
| Level 3 (Clinical Trial) | 3 | 0.5% |
| Level 4 (Observational) | 3 | 0.5% |
| Level 5 (Review/Case Report/Other) | 622 | 95.4% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| other | 其他 | 263 | 40.3% |
| metabolic | 代謝 | 158 | 24.2% |
| immune | 免疫調節 | 121 | 18.6% |
| cardiovascular | 心血管 | 89 | 13.7% |
| cognitive | 認知功能 | 66 | 10.1% |
| musculoskeletal | 肌肉骨骼 | 63 | 9.7% |
| digestive | 消化 | 55 | 8.4% |
| anti_aging | 抗衰老 | 53 | 8.1% |
| energy | 活力 | 48 | 7.4% |
| skin | 皮膚 | 21 | 3.2% |
| sexual | 性功能 | 8 | 1.2% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| vitamin B6 | 152 |
| iron | 94 |
| EPA | 84 |
| folate | 68 |
| vitamin B12 | 50 |
| calcium | 37 |
| magnesium | 35 |
| vitamin D | 35 |
| vitamin C | 34 |
| zinc | 33 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| vitamin B12 + vitamin B6 | 39 |
| iron + vitamin B6 | 36 |
| folate + vitamin B6 | 35 |
| folate + vitamin B12 | 29 |
| iron + zinc | 28 |
| calcium + iron | 27 |
| iron + magnesium | 27 |
| folate + iron | 26 |
| calcium + magnesium | 23 |
| calcium + zinc | 23 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 代謝 | 其他 | 心血管 | 免疫調節 | 活力 | 認知功能 |
|---|---|---|---|---|---|---|---|
| vitamin B6 | 152 | 67 | 42 | 34 | 23 | 12 | 23 |
| iron | 94 | 31 | 26 | 18 | 20 | 16 | 10 |
| EPA | 84 | 20 | 29 | 10 | 24 | 4 | 13 |
| folate | 68 | 23 | 22 | 16 | 12 | 8 | 9 |
| vitamin B12 | 50 | 15 | 15 | 11 | 8 | 6 | 7 |
| calcium | 37 | 8 | 11 | 7 | 3 | 12 | - |
| magnesium | 35 | 10 | 10 | 6 | 8 | 10 | 2 |
| vitamin D | 35 | 15 | 7 | 12 | 12 | 6 | 5 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 9 | 1.4% |
| Systematic Review | 9 | 1.4% |
| RCT | 6 | 0.9% |
| Clinical Trial | 3 | 0.5% |
| Observational | 3 | 0.5% |
| Review | 45 | 6.9% |
| Case Report | 26 | 4.0% |
| Other | 551 | 84.5% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Systematic Review of Nutrients’ Impact on Cognition and School Performance in School-Aged Children in Sub-Saharan Africa. — Nutrition reviews, 2026-03-13
- 功效分類：cardiovascular, cognitive
- Combined B-vitamin supplementation on homocysteine and vascular outcomes in coronary heart disease: a meta-analysis. — Annals of medicine, 2026-12-01
- 功效分類：cardiovascular, metabolic
- Branched-chain amino acid transferase 2 (BCAT2) deficiency: A case series and systematic review. — Molecular genetics and metabolism reports, 2026-03-01
- 功效分類：anti_aging, cognitive, metabolic
- Efficacy of B Vitamin Supplementation on Global Cognitive Function in Older Adults: A Systematic Review and Meta-analysis. — Nutrition reviews, 2025-12-01
- 功效分類：cognitive
- Effects of folic acid with vitamin B12/vitamin B6 intervention on serum homocysteine metabolism and complications in patients with type 2 diabetes: a systematic review and meta-analysis of randomized controlled trials. — Frontiers in nutrition, 2025-01-01
- 功效分類：metabolic
Level 2 證據（RCT）
- Serum Vitamin A Is Associated with Variations in the Relationship between Plasma B6 Vitamers and Cardiovascular Disease Risk. — The Journal of nutrition, 2026-01-01
- 功效分類：cardiovascular
- Impact of sustainable diets on micronutrient intakes and status: outcomes of the MyPlanetDiet randomized controlled trial. — The American journal of clinical nutrition, 2025-11-01
- 功效分類：energy
- Metabolomic characteristics of aqueous humor in young myopia patients without fundus complications. — Eye (London, England), 2026-02-01
- 功效分類：cardiovascular, metabolic
- Effects of bromelain supplementation on disease activity and quality of life in patients with ulcerative colitis: a randomized, triple-blind, placebo-controlled study. — Scientific reports, 2025-11-28
- 功效分類：other
- Antioxidant Treatment and the Chance to Conceive in Men Seeking Fertility Care: The SUMMER Randomized Clinical Trial. — JAMA network open, 2025-09-02
- 功效分類：anti_aging, sexual
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