維生素C文獻薈萃報告 — 2026 年 4 月

摘要

本月共收錄 維生素C 相關文獻 7847 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）168 篇，RCT 27 篇。

證據等級分布

證據等級	文獻數	佔比
Level 1 (Meta-Analysis/Systematic Review)	168	2.1%
Level 2 (RCT)	27	0.3%
Level 3 (Clinical Trial)	19	0.2%
Level 4 (Observational)	22	0.3%
Level 5 (Review/Case Report/Other)	7611	97.0%

功效分類統計

功效分類	中文	文獻數	佔比
other	其他	4238	54.0%
immune	免疫調節	1097	14.0%
cardiovascular	心血管	853	10.9%
metabolic	代謝	727	9.3%
anti_aging	抗衰老	715	9.1%
musculoskeletal	肌肉骨骼	503	6.4%
cognitive	認知功能	494	6.3%
energy	活力	435	5.5%
digestive	消化	270	3.4%
skin	皮膚	223	2.8%
sexual	性功能	128	1.6%

成分搭配統計

成分	文獻數
EPA	1001
iron	824
NAC	224
calcium	109
fiber	108
stem cell	77
zinc	73
collagen	71
glutathione	61
vitamin C	53

成分組合分析

以下列出最常被共同研究的成分組合：

成分組合	共同出現文獻數
EPA + iron	116
NAC + iron	33
EPA + NAC	27
fiber + iron	19
glutathione + iron	17
EPA + stem cell	16
EPA + fiber	16
EPA + calcium	16
exosome + exosomes	15
iron + vitamin C	13

成分功效分析

以下列出主要成分在各功效領域的研究文獻數：

成分	總文獻	其他	免疫調節	代謝	心血管	抗衰老	肌肉骨骼
EPA	1001	494	170	120	115	110	76
iron	824	433	126	79	65	74	34
NAC	224	120	35	18	29	17	15
calcium	109	38	15	14	22	14	24
fiber	108	46	10	8	6	15	20
stem cell	77	26	26	10	7	7	23
zinc	73	36	15	6	5	6	4
collagen	71	-	21	9	6	9	31

研究類型分布

研究類型	文獻數	佔比
Meta-Analysis	109	1.4%
Systematic Review	59	0.8%
RCT	27	0.3%
Clinical Trial	19	0.2%
Observational	22	0.3%
Review	255	3.2%
Case Report	230	2.9%
Other	7126	90.8%

近期重要文獻

Level 1 證據（Meta-Analysis / Systematic Review）

1. The Effect of Cranberry Consumption on C-Reactive Protein and Interleukin-6: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. — Food science & nutrition, 2026-02-01
   • 功效分類：immune
2. Evaluating Infections in Solid Organ Donors Before Transplantation: A Systematic Review of Clinical Practice Guidelines. — Transplantation, 2026-03-10
   • 功效分類：cardiovascular
3. Diet and nutrition in patients with neuromuscular disorders, as lifestyle factors affecting clinical parameters and quality of life: a narrative systematic review. — Nutrition research reviews, 2026-04-24
   • 功效分類：cardiovascular, immune, musculoskeletal
4. The clinical efficacy of pocket creation method ESD and conventional ESD in the treatment of early colorectal neoplasms: a meta-analysis. — Frontiers in medicine, 2026-01-01
   • 功效分類：other
5. Impact of Sarcopenia Index on Prognosis in Patients with Chronic Heart Failure. — Current medicinal chemistry, 2026-03-19
   • 功效分類：cardiovascular, immune, musculoskeletal

Level 2 證據（RCT）

1. Pharmacokinetics and Bioequivalence of 2 Deutetrabenazine Tablets in Healthy Chinese Volunteers Under Fasting and Fed Conditions. — Clinical pharmacology in drug development, 2026-03-01
   • 功效分類：skin
2. Short-duration phase-change material cryotherapy selectively enhances early neuromuscular and perceptual recovery. — PloS one, 2026-01-01
   • 功效分類：musculoskeletal, energy
3. Cost-effectiveness of transdiagnostic group cognitive behavioral therapy for emotional disorders in primary care: An analysis of the PsicAP clinical trial. — Journal of consulting and clinical psychology, 2026-02-01
   • 功效分類：cognitive
4. Effect of High-Fat Diet on Pharmacokinetics and Incidence of Adverse Reactions of Tacrolimus in Healthy Chinese Participants. — Clinical pharmacology in drug development, 2026-03-01
   • 功效分類：other
5. Effectiveness and safety of cyclosporine A in moderate to severe COVID-19: a randomized, open-label trial. — Scientific reports, 2026-02-17
   • 功效分類：immune

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