Vitamin D文獻薈萃報告 — 2026 年 2 月
摘要
本月共收錄 Vitamin D 相關文獻 447 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）28 篇，RCT 3 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 28 | 6.3% |
| Level 2 (RCT) | 3 | 0.7% |
| Level 3 (Clinical Trial) | 1 | 0.2% |
| Level 4 (Observational) | 8 | 1.8% |
| Level 5 (Review/Case Report/Other) | 407 | 91.1% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| musculoskeletal | 肌肉骨骼 | 157 | 35.1% |
| metabolic | 代謝 | 140 | 31.3% |
| immune | 免疫調節 | 123 | 27.5% |
| other | 其他 | 114 | 25.5% |
| cardiovascular | 心血管 | 81 | 18.1% |
| anti_aging | 抗衰老 | 54 | 12.1% |
| cognitive | 認知功能 | 38 | 8.5% |
| energy | 活力 | 37 | 8.3% |
| digestive | 消化 | 25 | 5.6% |
| sexual | 性功能 | 21 | 4.7% |
| skin | 皮膚 | 18 | 4.0% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| vitamin D | 408 |
| calcium | 118 |
| EPA | 46 |
| iron | 30 |
| zinc | 19 |
| magnesium | 16 |
| omega-3 | 14 |
| NAC | 13 |
| vitamin C | 10 |
| vitamin E | 10 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| calcium + vitamin D | 113 |
| EPA + vitamin D | 43 |
| iron + vitamin D | 27 |
| vitamin D + zinc | 17 |
| magnesium + vitamin D | 15 |
| omega-3 + vitamin D | 14 |
| calcium + iron | 12 |
| NAC + vitamin D | 12 |
| calcium + magnesium | 10 |
| vitamin C + vitamin D | 10 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 肌肉骨骼 | 代謝 | 免疫調節 | 其他 | 心血管 | 抗衰老 |
|---|---|---|---|---|---|---|---|
| vitamin D | 408 | 147 | 133 | 118 | 100 | 75 | 54 |
| calcium | 118 | 64 | 29 | 22 | 33 | 15 | 19 |
| EPA | 46 | 16 | 20 | 20 | 9 | 13 | 6 |
| iron | 30 | 8 | 9 | 11 | 12 | 4 | 4 |
| zinc | 19 | 6 | 9 | 10 | 1 | 4 | 4 |
| magnesium | 16 | 5 | 3 | 4 | 5 | 3 | 1 |
| omega-3 | 14 | 5 | 5 | 5 | 5 | 3 | 1 |
| NAC | 13 | 6 | 3 | 6 | 2 | 3 | 2 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 20 | 4.5% |
| Systematic Review | 8 | 1.8% |
| RCT | 3 | 0.7% |
| Clinical Trial | 1 | 0.2% |
| Observational | 8 | 1.8% |
| Review | 60 | 13.4% |
| Case Report | 32 | 7.2% |
| Other | 315 | 70.5% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Effectiveness and safety of bone protective interventions to mitigate bone loss and skeletal fractures experienced by patients with non-metastatic breast cancer: a systematic review and meta-analysis. — Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026-02-16
- 功效分類：musculoskeletal
- Nutritional Adequacy and Dietary Assessment Approaches in Institutionalised Older Adults Living in Long-Term Care Settings: A Systematic Review (2004-2024). — Nutrients, 2025-12-23
- 功效分類：metabolic, energy
- UV-Induced Nutritional Transformation of Mushrooms: From Molecular Shifts to Health Outcomes. — Food research international (Ottawa, Ont.), 2026-03-31
- 功效分類：other
- Low Dose Versus High Dose Vitamin D for Treatment of Nutritional Rickets: A Systematic Review and Meta-analysis. — Indian pediatrics, 2026-02-17
- 功效分類：other
- Analysis of the Additive Effects of Nutritional Strategies in Strength Training Interventions on Body Composition, Muscle Strength and Bone Mineral Density in Postmenopausal Women: A Systematic Review. — Sports medicine - open, 2026-01-14
- 功效分類：musculoskeletal
Level 2 證據（RCT）
- Vitamin D supplementation before in vitro fertilisation in women with polycystic ovary syndrome: multicentre, double blind, placebo controlled, randomised clinical trial. — BMJ (Clinical research ed.), 2026-02-17
- 功效分類：sexual
- Effect of standard versus long alimentary limb distal Roux-en-Y gastric bypass on weight loss and nutritional outcomes at 10 years in patients with BMI 50-60 kg/m2-a secondary analysis of a randomized clinical trial. — The British journal of surgery, 2025-12-24
- 功效分類：cardiovascular, metabolic
- Effect of vitamin D as Nutrition Supplement on Patients with Prolonged Ventilation due to Ventilator Associated Pneumonia and Sepsis Followed Severe Traumatic Lung Contusion: A Randomized Controlled Trial. — La Clinica terapeutica, 2026-01-01
- 功效分類：other
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