Vitamin D文獻薈萃報告 — 2026 年 6 月
摘要
本月共收錄 Vitamin D 相關文獻 1208 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）103 篇，RCT 12 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 103 | 8.5% |
| Level 2 (RCT) | 12 | 1.0% |
| Level 3 (Clinical Trial) | 1 | 0.1% |
| Level 4 (Observational) | 17 | 1.4% |
| Level 5 (Review/Case Report/Other) | 1075 | 89.0% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| musculoskeletal | 肌肉骨骼 | 405 | 33.5% |
| metabolic | 代謝 | 370 | 30.6% |
| immune | 免疫調節 | 360 | 29.8% |
| other | 其他 | 270 | 22.4% |
| cardiovascular | 心血管 | 194 | 16.1% |
| anti_aging | 抗衰老 | 135 | 11.2% |
| energy | 活力 | 106 | 8.8% |
| cognitive | 認知功能 | 99 | 8.2% |
| digestive | 消化 | 91 | 7.5% |
| skin | 皮膚 | 63 | 5.2% |
| sexual | 性功能 | 43 | 3.6% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| vitamin D | 1122 |
| calcium | 291 |
| iron | 131 |
| EPA | 117 |
| zinc | 56 |
| magnesium | 40 |
| folate | 37 |
| vitamin A | 36 |
| vitamin B12 | 33 |
| NAC | 32 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| calcium + vitamin D | 283 |
| iron + vitamin D | 124 |
| EPA + vitamin D | 110 |
| vitamin D + zinc | 52 |
| magnesium + vitamin D | 38 |
| folate + vitamin D | 36 |
| vitamin A + vitamin D | 35 |
| calcium + iron | 34 |
| vitamin B12 + vitamin D | 31 |
| EPA + calcium | 31 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 肌肉骨骼 | 代謝 | 免疫調節 | 其他 | 心血管 | 抗衰老 |
|---|---|---|---|---|---|---|---|
| vitamin D | 1122 | 384 | 353 | 346 | 241 | 180 | 130 |
| calcium | 291 | 167 | 91 | 52 | 62 | 38 | 43 |
| iron | 131 | 31 | 35 | 54 | 33 | 17 | 14 |
| EPA | 117 | 49 | 45 | 45 | 18 | 23 | 16 |
| zinc | 56 | 9 | 22 | 25 | 5 | 10 | 6 |
| magnesium | 40 | 13 | 10 | 10 | 12 | 8 | 3 |
| folate | 37 | 4 | 14 | 10 | 8 | 6 | 2 |
| vitamin A | 36 | 2 | 9 | 4 | 14 | 4 | - |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 66 | 5.5% |
| Systematic Review | 37 | 3.1% |
| RCT | 12 | 1.0% |
| Clinical Trial | 1 | 0.1% |
| Observational | 17 | 1.4% |
| Review | 174 | 14.4% |
| Case Report | 61 | 5.0% |
| Other | 840 | 69.5% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Systematic Review of Nutrients’ Impact on Cognition and School Performance in School-Aged Children in Sub-Saharan Africa. — Nutrition reviews, 2026-03-13
- 功效分類：cardiovascular, cognitive
- Effectiveness and safety of bone protective interventions to mitigate bone loss and skeletal fractures experienced by patients with non-metastatic breast cancer: a systematic review and meta-analysis. — Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2026-02-16
- 功效分類：musculoskeletal
- Dietary patterns, metabolic pathways and metainflammation in hidradenitis suppurativa: a systematic review. — Frontiers in immunology, 2026-01-01
- 功效分類：immune, metabolic, skin, digestive
- Erxian decoction for postmenopausal osteoporosis: An updated systematic review and meta-analysis. — Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry, 2026-05-07
- 功效分類：musculoskeletal
- Nutrition and rehabilitation after anterior cruciate ligament reconstruction: A systematic review. — Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2026-05-22
- 功效分類：musculoskeletal
Level 2 證據（RCT）
- Vitamin D supplementation before in vitro fertilisation in women with polycystic ovary syndrome: multicentre, double blind, placebo controlled, randomised clinical trial. — BMJ (Clinical research ed.), 2026-02-17
- 功效分類：sexual
- Effect of standard versus long alimentary limb distal Roux-en-Y gastric bypass on weight loss and nutritional outcomes at 10 years in patients with BMI 50-60 kg/m2-a secondary analysis of a randomized clinical trial. — The British journal of surgery, 2025-12-24
- 功效分類：cardiovascular, metabolic
- Effects of acupuncture on improving hormonal and metabolic biochemical characteristics in polycystic ovary syndrome. — African journal of reproductive health, 2026-03-16
- 功效分類：cardiovascular, immune, metabolic, sexual
- Lifestyle Intervention During Pregnancy Is Associated With Favourable Changes of Vitronectin in Women With Obesity: Results From the Randomised LiP Trial. — Clinical obesity, 2026-06-01
- 功效分類：metabolic
- Effects of oral nutritional supplement on growth and body composition in malnutrition at risk and malnourished children: MARVEL study, a multi-center randomized controlled trial. — European journal of nutrition, 2026-05-26
- 功效分類：energy
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