Vitamin E文獻薈萃報告 — 2026 年 4 月
摘要
本月共收錄 Vitamin E 相關文獻 526 篇，其中 Level 1 證據（Meta-Analysis/Systematic Review）38 篇，RCT 9 篇。
證據等級分布
| 證據等級 | 文獻數 | 佔比 |
|---|---|---|
| Level 1 (Meta-Analysis/Systematic Review) | 38 | 7.2% |
| Level 2 (RCT) | 9 | 1.7% |
| Level 3 (Clinical Trial) | 1 | 0.2% |
| Level 4 (Observational) | 1 | 0.2% |
| Level 5 (Review/Case Report/Other) | 477 | 90.7% |
功效分類統計
| 功效分類 | 中文 | 文獻數 | 佔比 |
|---|---|---|---|
| other | 其他 | 153 | 29.1% |
| immune | 免疫調節 | 133 | 25.3% |
| cardiovascular | 心血管 | 126 | 24.0% |
| metabolic | 代謝 | 100 | 19.0% |
| anti_aging | 抗衰老 | 70 | 13.3% |
| cognitive | 認知功能 | 50 | 9.5% |
| musculoskeletal | 肌肉骨骼 | 50 | 9.5% |
| skin | 皮膚 | 44 | 8.4% |
| digestive | 消化 | 40 | 7.6% |
| energy | 活力 | 36 | 6.8% |
| sexual | 性功能 | 22 | 4.2% |
成分搭配統計
| 成分 | 文獻數 |
|---|---|
| vitamin E | 427 |
| EPA | 84 |
| iron | 83 |
| vitamin C | 67 |
| vitamin A | 63 |
| selenium | 56 |
| vitamin D | 53 |
| zinc | 44 |
| glutathione | 30 |
| calcium | 29 |
成分組合分析
以下列出最常被共同研究的成分組合：
| 成分組合 | 共同出現文獻數 |
|---|---|
| iron + vitamin E | 72 |
| EPA + vitamin E | 72 |
| vitamin C + vitamin E | 60 |
| vitamin A + vitamin E | 56 |
| selenium + vitamin E | 52 |
| vitamin D + vitamin E | 50 |
| vitamin E + zinc | 39 |
| calcium + vitamin E | 27 |
| glutathione + vitamin E | 26 |
| vitamin A + vitamin D | 25 |
成分功效分析
以下列出主要成分在各功效領域的研究文獻數：
| 成分 | 總文獻 | 其他 | 免疫調節 | 心血管 | 代謝 | 抗衰老 | 活力 |
|---|---|---|---|---|---|---|---|
| vitamin E | 427 | 114 | 115 | 106 | 85 | 62 | 29 |
| EPA | 84 | 25 | 22 | 24 | 18 | 13 | 3 |
| iron | 83 | 20 | 18 | 31 | 17 | 8 | 10 |
| vitamin C | 67 | 15 | 16 | 13 | 18 | 13 | 10 |
| vitamin A | 63 | 30 | 10 | 9 | 14 | 6 | 6 |
| selenium | 56 | 12 | 13 | 14 | 12 | 7 | 10 |
| vitamin D | 53 | 23 | 11 | 9 | 11 | 7 | 5 |
| zinc | 44 | 7 | 11 | 8 | 13 | 9 | 8 |
研究類型分布
| 研究類型 | 文獻數 | 佔比 |
|---|---|---|
| Meta-Analysis | 26 | 4.9% |
| Systematic Review | 12 | 2.3% |
| RCT | 9 | 1.7% |
| Clinical Trial | 1 | 0.2% |
| Observational | 1 | 0.2% |
| Review | 67 | 12.7% |
| Case Report | 11 | 2.1% |
| Other | 399 | 75.9% |
近期重要文獻
Level 1 證據（Meta-Analysis / Systematic Review）
- Effects of vitamin supplementation on related symptoms in women with endometriosis: a systematic review and meta-analysis. — Annals of medicine and surgery (2012), 2025-07-01
- 功效分類：sexual
- Effects of different vitamins on individuals with septic shock: a Bayesian NMA of RCTs. — Frontiers in nutrition, 2025-01-01
- 功效分類：digestive
- The impact of almond supplementation on oxidative stress biomarkers: a systematic review and meta-analysis of randomized control trials. — Scientific reports, 2025-08-13
- 功效分類：other
- Comparative efficacy of multiple drugs for non-alcoholic fatty liver disease: a Bayesian network meta-analysis. — European journal of medical research, 2025-11-24
- 功效分類：metabolic
- Essential micronutrients and biguanides (metformin) synergistic and antagonistic interactions on neurocognitive outcomes in type two diabetes mellitus: a systematic review of preclinical and clinical evidence. — Frontiers in endocrinology, 2026-01-01
- 功效分類：cognitive, immune, metabolic
Level 2 證據（RCT）
- Reparative Effects of a Topical Antioxidant Serum Containing Vitamin C, Vitamin E, and Ferulic Acid After Ablative Fractional CO — Journal of cosmetic dermatology, 2026-01-01
- 功效分類：skin
- Effect of vitamin D and E supplementation on pain relief and premenstrual symptoms in primary dysmenorrhea: a randomized controlled trial. — BMC women’s health, 2025-09-29
- 功效分類：anti_aging
- Eleven-Year Outcomes of a Randomized Controlled Trial Comparing Standard and Distal Roux-en-Y Gastric Bypass in Patients with BMI Above 50 kg/m². — Obesity surgery, 2025-12-01
- 功效分類：metabolic, digestive
- Low wear with vitamin E-infused highly cross-linked polyethylene : 14 years’ follow-up of a randomized radiostereometric analysis study. — The bone & joint journal, 2025-11-01
- 功效分類：other
- The effect of early postpartum vitamin d and e supplementation on uterine after pain: a double-blind randomized clinical trial. — BMC women’s health, 2025-11-18
- 功效分類：other
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